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U6000AT+ Ultrasonic NebulizerThe U6000AT + adds a membrane desolvation module to the standard U5000AT + Ultrasonic Nebulizer for improved reduction of solvent-based interferences, particularly for volatile organic solvents (both polar and non-polar types).

Use with ICP-AES: For ICP-AES the U6000AT + is used primarily for the introduction of volatile organic solvents. These solvents can cause a number of serious problems: loss of plasma, plasma instability, high carbon emission background, and carbon buildup on the ICP torch.

Use with ICP-MS: For ICP-MS the U6000AT + can be used for both volatile organics and aqueous samples

Higher Nebulization Efficiency: The piezoelectric transducer of the U6000AT + converts more of the liquid sample into a usable aerosol, with an efficiency of 10-15%. With the membrane module connected, the result is a 2x to 5x enhancement of analyte signal vs. a standard pneumatic nebulizer.

Reduced Solvent-Based Interferences: The inert, fluoropolymer membrane desolvator reduces solvent based interferences from water and organic vapor. For example, the % CeO/Ce is typically <0.05% for water-based samples with the U6000AT +. Carbon-based inerferences such as 12C2+ are also greatly reduced, allowing detection of Mg at m/z = 24.

Improved Detection Limits: the combination of signal enhancement and reduced interferences enables lower instrument detection limits for both ICP-AES and ICP-MS.

Easy Setup: All U6000AT+ units are provided with an interface kit for quick and easy connection to the host ICP-AES or ICP-MS. The kit includes a nebulizer gas line and a sample out line with the appropriate ICP torch adapter. In addition, a rinse kit is included for cleaning the membrane desolvator.

Compact Design: The U6000AT + consists of the standard U5000AT+ Ultrasonic Nebulizer and a modular membrane desolvator box. The U5000AT + is simply placed on top of the desolvator box, conserving valuable benchtop space; the footprint of the U6000AT + is 35.6 cm W x 34.9 cm D.

Flexibility: The membrane desolvator module can be easily disconnected from the ultrasonic nebulizer if membrane desolvation is not necessary for a particular application. This feature allows stand-alone operation of the ultrasonic nebulizer.​

 Literature References

Publications showing our products in use. Click column headers to filter and sort. Links to third party sites.
Sequential Inductively Coupled Plasma Quadrupole Mass-Spectrometric Quantification of Radioactive Strontium-90 Incorporating Cascade Separation Steps for Radioactive Contamination Rapid Survey
Takagai et al.
Analytical Methods2014
Direct determination of lanthanides in environmental samples using ultrasonic nebulization and ICP OES
Bentlin and Pozebon
Journal of the Brazilian Chemical Society2010
Determination of Heavy Metals for the Quality Control in Argentinian Herbal Medicines by ETAAS and ICP-OES
Gomez et al.
Food and Chemical Toxicology2007
Chromium is the Proximate Clasogenic Species for Lead Chromate-Induced Clastogenicity in Human Bronchial Cells
Wise et al.
Mutuation Research2004
ICP Emission Spectrometry: A Practical Guide
Joachim Noelte
Determination of Scandium in River Water by ICP-OES with Flow-Injection On-Line Preconcentration Knotted Reactor and Ultrasonic Nebulization
Cerutti et al.
Journal of Analytical Atomic Spectrometry2003
A Rapid and Accurate Method for the Determination of Plutonium in Food Using Magnetic Sector ICP-MS with an Ultra-Sonic Nebulizer and Ion Chromatography
Evans et al.
Journal of Environmental Monitoring2003
Influence of Digestion Procedures on the Determination of Rare Earth Elements in Peat and Plant Samples by USN-ICP-MS
Krachler et al.
Journal of Analytical Atomic Spectrometry2002
Speciation Analysis of Antimony by High-Performance Liquid Chromatography Inductively Coupled Plasma Mass Spectrometry Using Ultrasonic Nebulization
Krachler and Emons
Analytica Chimica Acta2001
Speciation Preconcentration of Vanadium(v) and Vanadium(iv) in Water Samples by Flow Injection-Inductively Coupled Plasma Optical Emission Spectrometry and Ultrasonic Nebulization
Wuilloud et al.
Sulfur Profiles of the Twentieth Century in Peat Bogs of the Swiss Midlands Measured by IPC-OES and IC
Jeker and Krähenbühl
Determination of Technetium in Sea Water using Ion Exchange and ICP Mass Spectrometry with Ultrasonic Nebulization
Eroglu et al.
Determination of plutonium in seawater using co-precipitation and inductively coupled plasma mass spectrometry with ultrasonic nebulisation
Eroglu et al.
Spectrochimica Acta1998

 Application Notes

U6000_Boric_Acid.pdfAnalysis of Trace Elements in Boric Acid by ICP-MS
U6000_tech_note_a1001.pdfU6000AT+ Technical Note: Signal Enhancement and Interference Reduction for Quadrupole ICP-MS
USN_TECH_NOTE_U6002.pdfMeasurement of Silicon in Methyl Isobutyl Ketone (MIBK) using Ultrasonic Nebulization with Membrane Desolvation and ICP-AES Detection
USN_Tech_Note_U6003.pdfAnalysis of Isopropyl Alcohol (IPA) using Ultrasonic Nebulization with Membrane Desolvation and Quadrupole ICP-MS Detection
USN_TECH_NOTE_U6004.pdfDetermination of Wear-Metals in Lubricating Oil Using Ultrasonic Nebulization / Membrane Desolvation with ICP-AES Detection
PST010.pdfPoster: Optimization of Major and Trace Elements Determination in Acid Mine Drainage Water Samples by USN-ICP-OES
AP-U6000-003.pdfMeasurement of Trace Elements in Naphtha Using Ultrasonic Nebulization / Membrane Desolvation with ICP-AES Detection
AP-U6000-004.pdfReduction of Solvent-Based Interferences Using Ultrasonic Nebulization/Membrane Desolvation for Measurement of Trace Elements in Isopropyl Alcohol with Quadrupole ICP-MS Detection

 ‭(Hidden)‬ Application Areas

  • Polar organic solvents (ex. isopropyl alcohol)
  • Non-polar organic solvents (ex. naphtha, toluene)
  • Water-based samples for reduction of oxide and hydride interferences 

 Contact Us

​​Contact us using an​y of the methods below for more information on this or other Teledyne CETAC products.


Toll Free: 1-800-369-2822

International: +1 402-733-2829​​


Specification ​Title Specification Details
Sample Uptake Rate 0.5 - 2.5 ml/min
Nebulizer Gas Flow 0.5 - 1.5 L/min
​Heater Temperature 120ºC to 160ºC 
​Cooler Temperature -20ºC to +10ºC 
​Membrane Oven Temperature 80ºC to 160ºC 
​Voltage Ultrasonic Nebulizer 100-120 VAC, 50/60Hz, 4.5A
220-240 VAC, 50/60Hz, 2.5A
Voltage Membrane Desolvator ​100-​240 VAC, 50/60Hz, 4A/2/A​
Height 38.7 cm (15.25 in.)
Width ​35.6 cm (14 in.)
Depth 34.9 cm (13.75 in.)
Weight 13.6 kg) (29.9 lbs)
Warranty 12 month limited​