HDIP software is feature-rich to provide a fast and flexible platform for large, complex image processing in a straightforward, intuitive workspace. HDIP can handle data from a broad range of LA-ICP-MS instrumentation as well as from other microscopy techniques. The workspace contains all elemental images and optical images and images of any source can be layered on top of each other and aligned.​

AutoPilot data proce​ssing


Allows HDIP to process data fully-autonomously from raw data towards the end-stages of data processing. AutoPilot will import data, synchronize LaserTrace and ICP-MS data, apply multiple corrections, reconstruct and calibrate the data, and export the data as publication-ready figures. The use of AutoPilot is optional.

Color m​​ap editor

A full-fledged false color map editor can be used to attribute any of the dozens of false lookup tables to an image. Furthermore, the lookup table can be scaled linear, logarithmic or using a CDF. The range of selected values is selected on a histogram. Additional to​ols allow the user to adjust transparency, scaling and thresholding. Any combination of channels can be used to make RGB composites.

Mutli-calibr​​ant quantification

Multi-standard external calibration can be applied to compute quantitive elemental images. A database of standard and certified reference materials is included. HDIP can even automatically recognize standards by the name of the sample provided by the user, greatly streamlining the calibration process. internal standardization, 100% oxide normalization, complete error propagation and limit of detection calculations are available.

Spatial and temp​​oral deconvolution

deconvolution-tool.png ​
​Retrieve better spatial resolution with built-in convolution, deconvolution, and denoising tools. For example, a peak profile of a single laser shot can be used to correct for blurring effects which are caused by washout. Or better resolution can be extracted by accounting for spot position overlap.

Publication-qua​​lity graphics

HDIP can export publication-quality graphics with customizable layout. Your latest layout is stored in your profile, so you can have a consistent layout across your report or manuscript. It is also possible to export images as raw .TIFF files and .CSV files.

Image segm​entation

HDIP has a large toolset for image segmentation. The segmentation of the zones, cells, samples and features within the elemental image can be performed manually, using various drawing, flooding and selection tools, or automatically, based on clustering zones within the sample, or based on an image recognition suite. This for example allows HDIP to automatically extract single cell data from an image.

Additio​​nal Features

* Signal peaks can be automatically detected, and peak analysis can be perfomed, which provides information on the peak area, maxima, width of each peak. * Channel calculator which allows to apply your own formulas on the values: add, subtract, multiply or ratio different mass channels with ease. * 3D viewer allows to explore 3D data.

Why we created ​HDIP

HDIP was initially developed by academic researchers to fill the need for a high-quality and powerful data processing and visualization tool for time-resolved mass spectrometry data, which does not rely on third-party software. HDIP is now being used as a development platform for cutting-edge reseach in the mass spectrometry field and as a reliable, qualitative and productive tool for routine approaches.The need for software build upon an open data format such as HDF was crucial here, as the data should remain accessible via interfaces of many programming languages, such as C, C++, python, R, Matlab, Java and others.

​Our Mission

  • We strive to deliver the most advanced laser ablation - inductively coupled plasma - mass spectrometry data processing and analysis tool available.
  • Fast and strong user support is very important. All members of the support team have an academic background with years of experience in the field, for fundamental research as well as application-oriented research in a number of field such as bulk analysis, geochronology, isotope systems, and imaging.
  • Have a problem you can't fix? Have an new idea on how to process data? Your ICP-MS produces data that can't be imported? We are there for you to create a solution.
  • In development since 2015

Yours sincerely, Stijn J. M. Van Malderen, Senior developer of HDIP​

​​​List of features in HDIP:

  • ​Data import: Data can be imported from a broad range of LA-ICP-MS instrumentation and other microscopy techniques.
  • Project-based data structure: data and metadata, including images, are stored in an open format HDF5 file. 
  • Automatic raw data backup
  • Data export
  • Streamlined image reconstruction and LaserTrace analysis
  • AutoPilot: fully automated image reconstruction.
  • Preview: inspect your data intermittently during a run
  • Optimize: predict the settings of your ICP-MS prior to mapping
  • Specialized data reduction methods
  • Advanced background correction methods
  • Drift correction based on bracketing
  • Data restoration approaches: convolution, deconvolution and denoising
  • Advanced false color map editor
  • 3D viewer
  • 3D image reconstruction by 2D slice registration
  • Manual and automated voxel selection
  • Multi-standard external calibration with internal standardization
  • Multivariate data analysis
  • Binary Masking
  • Image filtering
  • Manual/Automatic peak integration and peak analysis
  • Outlier rejection
  • Channel calculator.
  • Matrix transforms: arrays can be cropped, expanded, rotated, transposed, scaled, flipped,…
  • Spreadsheet tool​