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Designed by scientists for scientists
​Available for Teledyne Photon Machines Laser Systems​

HDIP is a full-featu​red laser ablation mass spectrometry software suite that enables scientists to quickly and efficiently produce detailed high-quality data output for a plethora of experiment types ranging from elemental bulk composition analysis to high-speed elemental micro- and nano-scale imaging. Originally developed to simplify, automate and accelerate the management of the large datasets in laser ablation ​ICP-MS imaging applications, the software suite has been expanded to offer an incredibly flexible suite of features addressing the ever-expanding range of capabilities demanded by modern analytical laboratories.

​New Feat​ure​s in Version 1.6

​HD​​IP 1.6 introduces LaOptimize, a new tool that fully optimizes your system according to ap​plication and sample.



This wizard guides you to optimize your system fully for your specific application and ample. Based on a small test scan, the software will suggest the best conditions for analysis. Works for both imaging applications and bulk analysis.


Select Sample Matrix​​​

LaOptimize accomodates many sample types, including tissue, bone, glass, carbonate, micas, phosphates, quartz, sulphides, pellets, nanoparticles, ice, and more.

Optimization Goals​​​

Based on user input, a different optimization goal will be set for the system parameters.​ Optimize based on spatial resolution, best sensitvity, defined dosage, spot size and runtime, and more.


Detailed Simulation​​​​

Recommended ​parameters are presented with simulations of how the signal will look according to the suggested settings.

Version 1.6 also introduces a number of new features to improve bulk analysis workflow.


​​​Automatic Noise Rejection​​​

​​A new bulk analysis tool automatically filters sample replicates and "bad regions" within a scan. It can work autonomously on a set of recording based on a set of rejection parameters. QC tools report anomalies with fully configurable warning and error levels.​


Segment Investigation​​​

When selecting a new zone of an elemental image, the signal distribution and elemental fingerprint are shown in two new graphs. This allows you to look at REE patterns in the image and inspect inclusions.​


Isotope-specific Calibration​​​

HDIP ​now takes into account the isotopic composition of the standards during calibration. This increases accuracy and allows the concentration of individual isotopes and the element to be determined.​


Custom Spreadsheet Export​​​

A new tool for creating and exporting custom spreadsheets in any format. Save format templates for a repeatable workflow.

Unlock Your​ Raw Data​

HDIP is designed to unlock the full potential of your LA-ICP-MS system for increasingly complex LA-ICP-MS applications. Working with all the major commercially available ICP-MS vendors, your data can be imported loss-less into HDIP with 64-bit accuracy. A virtual workspace provides a visual simulation of the sample environment and brings together all MS output, laser system images, and ​​imported CL, FM or microprobe images, and allows this information to be fused and combined. Batch processing is available for TOF image formats (TOFWERK AG icpTOF and Nu Instruments Ltd. Vitesse).background-large-figure.png

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Create Amazing Images

HDIP simplifi​es image generation by producing fully calibrated multi-mega-pixel elemental/isotopic image maps. HDIP can produce images from any combination of laser patterns, with omnidirectional support, as well as arbitrary shapes of the ablation zone, using one of 5 advanced image reconstruction algorithms.


Advanced Ima​ge Analysis

With the advanced image analysis tools available in HDIP, you can interrogate the elemental distribution in multi-mega-pixel images with hundreds of mass channels and gain deep insights in relational patterns between sub-domains in your multi-phase image. Automated segmentation and image feature recognition allow to dissect the image and extract particles, boundary mixing ​layers, cells, inclusions, anatomical regions, layered chronological records, or metallic contaminations​.​

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​Reliability an​d Flexibility

Whether you are interested in ultra-trace levels or major levels, HDIP offers a solution for a semi/fully quantitative elemental characterization for any matri​x. Dedicated QA/QC and data correction tools within HDIP ensure high data quality and reliability can be maintained d​​uring the data reduction process. The combination of multi-calibrant calibration curves, internal standardization, 100% oxide normalization, complete error propagation and limit of detection calculations within HDIP allow for complex experiment designs. These tools are complemented with automation and template-based batch processing, enabling routine analysis of 1000's of samples and images.​​​


Always I​​​​mproving​​

Continuous development of the HDIP software suite assures it remains at the bleeding edge of mass spectrometry. HDIP is designed with ​the help of academic partners and the latest data analysis approaches are being incorporated into the software. Fast support by experts around the world is available to help users and guide them through the software step-by-step.​


Why We Created HDIP

HDIP was initially developed by academic researchers to fill the need for a high-quality and powerful data processing and visualization tool for time-resolved mass spectrometry data, which does not rely on third-party software. HDIP is now being used as a development platform for cutting-edge reseach in the mass spectrometry field and as a reliable, qualitative and productive tool for routine approaches.The need for software build upon an open data format such as HDF was crucial here, as the data should remain accessible via interfaces of many programming languages, such as C, C++, python, R, Matlab, Java and others.

​We strive to deliver the most advanced laser ablation - inductively coupled plasma - mass spectrometry data processing and analysis tool available. Fast and strong user support is very important. All members of the support team have an academic background with years of experience in the field, for fundamental research as well as application-oriented research in a number of field such as bulk analysis, geochronology, isotope systems, and imaging. Have a problem you can't fix? Have an new idea on how to process data? Your ICP-MS produces data that can't be imported? We are there for you to create a solution.

Yours sincerely,
Stijn J. M. Van Malderen, Senior developer of HDIP​​​​

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 Contact Us

​​Contact us using an​y of the methods below for more information on this or other Teledyne CETAC products.

Toll Free: 1-800-369-2822

International: +1 402-733-2829​​​​

Or visit the HDIP Support Page​​​​    ​​​

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​Powerful Simplicity


The most powerful LA-ICP-MS imaging software on the market today

Analyte Excite Excimer Laser Ablation System

  • Fully Automated Image Optimization for ​Highest Resolution and Sensitivity

  • Autopilot One-Click Image Generation

  • Natively Accepts All Major ICP-MS File Formats

HDIP (HDF-based Image Processing) is a software platform designed to process imaging data stored in the HDF5 format. HDF5 is a popular, efficient, highly versatile format for storing large volumes of data in a variety of scientific fields.

The platform has a special toolkit specifically designed to process transient mass spectrometry data, with a specific emphasis on laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) imaging. This toolkit allows users to process complex LA-ICP-MS datasets in a reliable, transparent, and consistent manner in a matter of minutes. 


Basic and advanced algorithms are provided to process the data, and 2D and 3D data visualization and inspections tools enable the user to investigate the data in-depth. HDIP can export the results in publication-quality figures, animations, and many data formats. The platform was built from the ground up, and does not rely on third party frameworks like MATLAB or Igor Pro. Because the data format upon which the library can be readily inspected by many 3rd party tools, your data and meta-data is kept intact in a future-proof, self-describing, safe container.

​New Feat​ure​s in Version 1.5

​​Version 1.5​+ inc​​ludes a fresh new look, improvements to existing features, as well as completely new modules.


Improv​ed layout and project browser for a more efficient workflow.

A completely overhauled background correction module now features automatic bi-cubic backgrounding modeling, increasing accuracy and decreasing user-intervention.

A new mathematical interference correction module was added to correct mass channel intensities using a proxy intensity from a different mass channel. Support for polyatomic, isobaric, as well as abundance sensitivity correction is present.​

New tools were added to the labeled segment editor. For example, the "paintbrush" tool can be used to freehand draw segments within an image.

Automatic cross-calibration of references and samples of different measurement conditions has been added. HDIP can now successfully account for changes in repetition rate, spot size and shape within an experiment, in external calibration.

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