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​​​For HelE​x II equipped laser systems​​   

  • Capture single-shot events
  • Hi-Res sample maps
  • Ultrafast washout and reduced sampling time 
The Aerosol Rapid Introduction System (ARIS) connects a HelEx II laser ablation cell to an ICP-MS instrument with minimal transfer volume. The ARIS delivers the sample directly to the torch without the use of internal valves, providing fast washout.

aris-diagram.jpgThe ARIS kit is a set of components designed to reduce the dead volume inside the cell and up to the torch to fully utilize the performance characteristics of the standard HelEx II cell. The use of thin PEEK tubing has the added benefit of being insensitive to moderate bends in the transfer line so that peak shape and fractionation performance is maintained from all areas of the cell.


Combined wash-in and wash-out times of < 20 ms allow the user to resolve individual single pulses at sample rates of up to 30 Hz for biological materials and up to 60 Hz for geological materials.


​Compilation of raw transient signals of the laser firing while raster scanning an area at 20, 40 and 60 Hz, showing baseline separation of individual laser pulses using the HelEx II 2-volume cell (courtesy of the University of Ghent).

 Application Notes

Click column headers to filter and sort.
TN-AnalyteG2-003.pdfHigh‐speed sub‐micrometer imaging of sub‐cellular structures in single cells using ARIS
AP-ANALYTEG2-001.pdfHigh-Speed, High-Resolution, Multi-Element Imaging of Plant Root Cross-Sections to Highlight Nutrient Transport Pathways
AP_ARIS_cisplatin.pdfApplication of the ARIS for high-resolution LA-ICP-MS 2D Pt-mapping for revealing cisplatin-induced nephrotoxic side effects

 Literature References

Publications showing our products in use. Click column headers to filter and sort. Links to third party sites.
Ablation Chamber
Laser (nm)
Mass Spec
Van Acker et al.
High-resolution Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging of Cisplatin-Induced Nephrotoxic Side EffectsAnalytica Chimica ActaHelEx-II193 nmQBiologicalGhent University
Van Malderen et al.
Quantitative determination and subcellular imaging of Cu in single cells via laser ablation-ICP-mass spectrometry using high-density microarray gelatin standardsAnalytical ChemistryHelEx-II193 nmQBiologicalGhent University
Zhou et al.
LA-ICP-MS elemental mapping of pyrite : An application to the Palaeoproterozoic atmospherePrecambrian ResearchHelEx-II193 nmQGeologicalTrinity College Dublin
Bussweiler et al.
Laser Ablation and Inductively Coupled Plasma – Time-of-Flight Mass Spectrometry — A Powerful Combination for High-Speed Multielemental Imaging on the Micrometer ScaleSpectroscopyHelEx-II193 nmTOFFundamentalsTOFWERK
Van Malderen et al.
Imaging the 3D trace metal and metalloid distribution in mature wheat and rye grains via laser ablation-ICP-mass spectrometry and micro-X-ray fluorescence spectrometryJournal of Analytical Atomic SpectrometryHelEx-II193 nmQBiologicalGhent University
Theiner et al.
Fast high-resolution LA-ICP-MS imaging of the distribution of platinum- based anti-cancer compounds in multicellular tumor spheroidsAnalytical ChemistryHelEx-II193 nmQBiologicalUniversity of Vienna
Van Malderen et al.
Three-dimensional reconstruction of the tissue-specific multi-elemental distribution within Ceriodaphnia dubia via multimodal registration using laser ablation ICP-mass spectrometry and X-ray spectroscopic techniquesAnalytical ChemistryHelEx-II193 nmTOFBiologicalGhent University
Costas-Rodriguez et al.
Laser ablation-inductively coupled plasma-mass spectrometry for quantitative mapping of the copper distribution in liver tissue sections from mice with liver disease induced by common bile duct ligationJournal of Analytical Atomic SpectrometryHelEx-II193 nmQBiologicalGhent University
Petrus et al.
A new approach to laser-ablation inductively-coupled-plasma mass-spectrometry (LA-ICP-MS) using the flexible map interrogation tool ‘Monocle’Chemical GeologyHelEx-II193 nmQSoftwareTrinity College Dublin
Stead et al.
Rare earth element partitioning and subsolidus exchange behaviour in olivineChemical GeologyHelEx-II193 nmQGeologicalTrinity College Dublin
Van Malderen et al.
Considerations on data acquisition in laser ablation-inductively coupled plasma-mass spectrometry with low-dispersion interfacesSpectrochimica Acta Part BHelEx-II193 nmQFundamentalsGhent University
Ronzani et al.
Capabilities of laser ablation – ICP-TOF-MS coupling for isotopic analysis of individual uranium micrometric particlesJournal of Analytical Atomic SpectrometryHelEx-II193 nmTOFGeologicalCommissariat Energie Atomique
Craig et al.
Doubling Sensitivity in Multicollector ICPMS Using High-Efficiency, Rapid Response Laser Ablation TechnologyAnalytical ChemistryHelEx-II193 nmMCFundamentalsThermo Fisher Scientific, Bremen
Drost et al.
An image mapping approach to U-Pb LA-ICP-MS carbonate dating and applications to direct dating of carbonate sedimentationGeochemistry, Geophysics, GeosystemsHelEx-II193 nmQGeologicalTrinity College Dublin
Gonzalez de Vega et al.
MMP-11 as a biomarker for metastatic breast cancer by immunohistochemical-assisted imaging mass spectrometryAnalytical and Bioanalytical ChemistryHelEx-II213 nmQBiologicalUniversity of Oviedo
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