The emergence of metallomic applications in the late 1990’s has rapidly evolved and given rise to a need to determine a wide range of trace metal concentrations in various biological materials. In early studies samples of cancerous material were analyzed for metal tags to help scientists understand the effectiveness of key drug components, but as the science evolved there is now an increasing interest in determining the trace metal content of single cells, bio-fluids, and to understand the role of metals in human health and disease treatment. On top of this there is also considerable interest in the presence of metal nanoparticles in tissue material, as well as high resolution single µm resolution elemental image maps of biological samples generated by laser ablation.

Teledyne CETAC offers a variety of specialist liquid sample automation specifically engineered to allow the analysis of low volume bio-fluids and single cells by ICP-MS, as well as highly evolved laser ablation technology to enable high speed, high resolution quantifiable elemental concentration maps of many biomaterials to be produced.

     Application Notes

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    HAM0850.pdfMicrolab® 600 Diluter Versatile Tool for Handling Hyaluronic Acid SolutionsSimPrep04/18/2018
    AP-MVX7100-003.pdfComparison of the MVX‐7100 Micro‐Volume Workstation with an Established Laboratory Method for the Assessment of Lead, Mercury, and Arsenic in Human Whole BloodMVX-710004/20/2016
    USN_TECH_NOTE_U5005.pdfEnhanced Elemental Detection for Axial-Viewing Inductively Coupled Plasma - Optical Emission Spectrometry (ICP-OES) with Ultrasonic NebulizationU5000AT04/20/2016
    USN_TECH_NOTE_U5006.pdfEnhanced Arsenic Detection in a Biological Sample for Axial-Viewing Inductively Coupled Plasma - Optical Emission Spectrometry (ICP-OES) With Ultrasonic NebulizationU5000AT04/20/2016
    PST2013_LowInjectionAS.pdfPoster: A Low Volume Injection Autosampler For ICP-MSDS-5; MVX-710004/20/2016
    PST2014_WPC_FlowInjectionAS_clawed-frog.pdfPoster: Novel Low Volume Autosampler for ICP-MSMVX-710004/20/2016
    PST2015_Nanolytica.pdfPoster: Nanoparticle Mapping in Tissues by LA-ICP-MSHelEx II; LSX-213 G204/20/2016
    PST025.pdfPoster: Optimizing Ablation Cells and Aerosol Transport Systems for Laser Ablation ICP-MSHelEx II04/20/2016
    PST2019_Metallomics_Intro-to-Single-Cell.pdfAn Introduction to the Science of Single Cell Analysis with ICP-MS InstrumentationMVX-710006/28/2019
    PST2016_Goldschmidt_AridusII.pdfPoster: Multicollector ICP-MS with a Desolvating Nebulizer System for U-Series Dating of Late Pleistocene Terrestrial SnailsAridus II07/26/2018
    AP-ASX560-001.pdfHigh Throughput Automation of the ÄKTA™ pure 25 via the ASX-560ASX-56008/30/2016
    TN-AnalyteG2-003.pdfHigh‐speed sub‐micrometer imaging of sub‐cellular structures in single cells using ARISAnalyte G2; ARIS10/02/2017
    BioRad_Bulletin_6896.pdfIntegrating the CETAC ASX-560 Autosampler with the NGC™ Chromatography SystemASX-56012/15/2017
    BioRad_Bulletin_6879.pdfIncreasing Throughput of a Tandem mAb Purification by Adding a High-Volume Autosampler to the NGC™ Chromatography SystemASX-56012/15/2017