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 Application Notes

U6000_Boric_Acid.pdfAnalysis of Trace Elements in Boric Acid by ICP-MS
U6000_tech_note_a1001.pdfU6000AT+ Technical Note: Signal Enhancement and Interference Reduction for Quadrupole ICP-MS
USN_TECH_NOTE_U6002.pdfMeasurement of Silicon in Methyl Isobutyl Ketone (MIBK) using Ultrasonic Nebulization with Membrane Desolvation and ICP-AES Detection
USN_Tech_Note_U6003.pdfAnalysis of Isopropyl Alcohol (IPA) using Ultrasonic Nebulization with Membrane Desolvation and Quadrupole ICP-MS Detection
USN_TECH_NOTE_U6004.pdfDetermination of Wear-Metals in Lubricating Oil Using Ultrasonic Nebulization / Membrane Desolvation with ICP-AES Detection
PST030.pdfPoster: Use of Enhanced Nebulizer Systems for Very Hard Water Analysis Using ICP-AES Detection
PST010.pdfPoster: Optimization of Major and Trace Elements Determination in Acid Mine Drainage Water Samples by USN-ICP-OES
AP-U6000-003.pdfMeasurement of Trace Elements in Naphtha Using Ultrasonic Nebulization / Membrane Desolvation with ICP-AES Detection
AP-U6000-004.pdfReduction of Solvent-Based Interferences Using Ultrasonic Nebulization/Membrane Desolvation for Measurement of Trace Elements in Isopropyl Alcohol with Quadrupole ICP-MS Detection

 ‭(Hidden)‬ Application Areas

  • Polar organic solvents (ex. isopropyl alcohol)
  • Non-polar organic solvents (ex. naphtha, toluene)
  • Water-based samples for reduction of oxide and hydride interferences 

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International: +1 402-733-2829​​


Specification ​Title Specification Details
Sample Uptake Rate 0.5 - 2.5 ml/min
Nebulizer Gas Flow 0.5 - 1.5 L/min
​Heater Temperature 120ºC to 160ºC 
​Cooler Temperature -20ºC to +10ºC 
​Membrane Oven Temperature 80ºC to 160ºC 
​Voltage Ultrasonic Nebulizer 100-120 VAC, 50/60Hz, 4.5A
220-240 VAC, 50/60Hz, 2.5A
Voltage Membrane Desolvator ​100-​240 VAC, 50/60Hz, 4A/2/A​
Height 38.7 cm (15.25 in.)
Width ​35.6 cm (14 in.)
Depth 34.9 cm (13.75 in.)
Weight 13.6 kg) (29.9 lbs)
Warranty 12 month limited​


The U6000AT+ adds a membrane desolvation module to the standard U5000AT+ Ultrasonic Nebulizer for improved reduction of solvent-based interferences, particularly for volatile organic solvents (both polar and non-polar types).

Use with ICP-AES:  For ICP-AES the U6000AT+ is used primarily for the introduction of volatile organic solvents.  These solvents can cause a number of serious problems: loss of plasma, plasma instability, high carbon emission background, and carbon buildup on the ICP torch.

Use with ICP-MS:  For ICP-MS the U6000AT+ can be used for both volatile organics and aqueous samples

Higher Nebulization Efficiency:   The piezoelectric transducer of the U6000AT+ converts more of the liquid sample into a usable aerosol, with an efficiency of 10-15%.  With the membrane module connected, the result is a 2x to 5x enhancement of analyte signal vs. a standard pneumatic nebulizer.

Reduced Solvent-Based Interferences:  The inert, fluoropolymer membrane desolvator reduces solvent based interferences from water and organic vapor.  For example, the % CeO/Ce is typically <0.05% for water-based samples with the U6000AT+.  Carbon-based inerferences such as 12C2+ are also greatly reduced, allowing detection of Mg at m/z = 24.

Improved Detection Limits:  the combination of signal enhancement and reduced interferences enables lower instrument detection limits for both ICP-AES and ICP-MS.

Easy Setup:  All U6000AT+ units are provided with an interface kit for quick and easy connection to the host ICP-AES or ICP-MS.  The kit includes a nebulizer gas line and a sample out line with the appropriate ICP torch adapter.  In addition, a rinse kit is included for cleaning the membrane desolvator.

Compact Design:  The U6000AT+ consists of the standard U5000AT+ Ultrasonic Nebulizer and a modular membrane desolvator box.  The U5000AT+ is simply placed on top of the desolvator box, conserving valuable benchtop space; the footprint of the U6000AT+ is 35.6 cm W x 34.9 cm D.

Flexibility:  The membrane desolvator module can be easily disconnected from the ultrasonic nebulizer if membrane desolvation is not necessary for a particular application.  This feature allows stand-alone operation of the ultrasonic nebulizer.

Optional Blend Gas Accessory:  An optional blend gas accessory, the CETAC BGX-100, is available to help prevent carbon build-up on the ICP torch and ICP-MS sampling cones during extended introduction of volatile organic solvents.